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COVID-19 Vaccination Information for Hospitals

Note: In addition to providing general information about the vaccination process in South Carolina, many of these resources speak specifically to the Pfizer Vaccine. For information about the Moderna vaccine, click here.

If you are an individual looking for contact and scheduling information on getting a vaccine at your local hospital, that list is available here

Emergency Use Authorization for Pfizer Vaccine

The FDA has currently granted Emergency Use Authorization to Pfizer for its COVID-19 vaccine. This AHA Bulletin contains the EUA as well as helpful information for providers and patients. This fact sheet from the FDA provides additional information for healthcare providers administrating the vaccine. A related fact sheet for caregivers and recipients is also available (translations of this fact sheet are available here.)

CDC Advisory Committee  Interim Recommendation for Use of Pfizer-BioNTech COVID-19 Vaccine

On December 12, 2020, after an explicit, evidence-based review of all available data, the CDC Advisory Committee on Immunization Practices (ACIP) issued an interim recommendation for use of the Pfizer-BioNTech COVID-19 vaccine in persons aged ≥16 years for the prevention of COVID-19. Their evidence for recommendation is available here.

The recommendation for the Pfizer-BioNTech COVID-19 vaccine should be implemented in conjunction with ACIP’s interim recommendation for allocating initial supplies of COVID-19 vaccine.

New COVID-19 Training Module for Healthcare Providers. The CDC has created a new web-on-demand, self-paced training module for healthcare providers who will be administering the Pfizer-BioNTech COVID-19 vaccine. This module will provide information on storage, handling, preparation, administration, and documentation of the Pfizer-BioNTech COVID-19 vaccine. Continuing education will be available for this module.

Pfizer Vaccine General Resources

Contents and Quantities for Mega Kits to Support Pfizer Vaccine

McKesson Customer Service recently published this clarification about the needle and syringes included in the COVID-19 ancillary supply kits for administering the Pfizer vaccine based on questions coming into our call centers.  There is some confusion about the quantities of needles and syringes included in the kits. Each kit is clearly labeled with a complete inventory list.

Direct Ship Site Pfizer Deliveries

Primary vaccine coordinators for direct ship locations should receive emails regarding ancillary supplies and vaccine shipments. Please ensure you have communicated the emails below to your IT security teams:

Phase 1a Guidance for COVID-19 Vaccine Allocation

DHEC has released guidance for those included in the Phase 1a allocation, which includes staff and residents of nursing homes and long-term care facilities and people serving in healthcare settings. Acute care hospitals will receive the first doses of the vaccine so that they can begin vaccinating their Phase 1a staff in the coming days. DHEC advises all others who are included in Phase 1a but not employed by hospitals to contact DHEC at for information on when and how to receive the vaccine. SCHA is also encouraging hospitals to begin thinking about how to assist their local EMS agencies with vaccine administration.

DHEC recognizes that no two healthcare facilities are the same and that critical workers in high-risk settings will vary in different facilities depending on their staffing and community conditions and needs. The Phase 1a Guidance for COVID-19 Vaccine Allocation was developed to offer guidance to healthcare facilities and their staff concerning evaluating risk but avoiding being overly proscriptive in the allocation of vaccine. For more information, including contact information for questions, please see this letter and guidance from DHEC.

COVID-19 Vaccine Provider Enrollment

To receive and administer the coronavirus vaccine and supplies, providers have to enroll in a federal vaccine distribution program, coordinated through the state’s immunization program (unless they are part of a national chain that registered directly with the CDC). The federal government will procure and distribute the vaccine at no cost to enrolled providers. Questions? Please email:

VaccineFinder Reporting

The COVID-19 Vaccination Program Provider Agreement requires providers to report vaccine supply information as directed by CDC. Locations receiving COVID-19 vaccine should report supply information daily (Mon-Sun) to VaccineFinder using the online COVID Locating Health Provider Portal. Vaccination providers can report manually via the secure COVID Locating Health Provider Portal, or via an automated secure data transfer directly to the COVID Locating Health Platform.

Once enrolled in DHEC’s COVID-19 Vaccination Program, the section A organization point of contact will receive an email from prompting them to complete their account registration in VaccineFinder and determine the desired reporting method for their organization. Questions? Please email:

Vaccine Administration Management System (VAMS)

VAMS is a secure, web-based tool built to help SC DHEC, vaccination clinics, organizations/employers, and vaccine recipients manage COVID-19 vaccination efforts during phase 1(limited vaccine supply). It supports operations and data collection and tracking to meet CDC, Operation Warp Speed (OWS), and South Carolina DHEC COVID-19 vaccination requirements. DHEC’s Phase 1 providers will register their clinic information in VAMS, SC employers and organizations with priority populations (TBD) will register their phase 1 populations in VAMS, and phase 1 populations will register for vaccination services at phase 1 clinic locations in VAMS.

DHEC will activate phase 1a and phase 1b providers and onboard them to VAMS. Primary vaccine coordinators listed on activated phase 1a and 1b vaccine provider section B forms can expect an outreach call from DHEC’s VAMS Onboarding team. Coordinators will receive a subsequent onboarding email from to activate their account in VAMS and register their clinic information. More information is forthcoming as DHEC’s vaccination efforts evolve. More resources are available via DHEC. Email with any additional questions.

Vaccine Adverse Event Reporting (VAERS)

The vaccination provider is responsible for mandatory reporting of the following to the Vaccine Adverse Event Reporting System (VAERS):

  • vaccine administration errors whether or not associated with an adverse event,
  • serious adverse events (irrespective of attribution to vaccination),
  • cases of Multisystem Inflammatory Syndrome (MIS) in adults and children, and
  • cases of COVID-19 that result in hospitalization or death.

Complete and submit reports to VAERS online at or by calling 1-800-822-7967. The reports should include the words “Pfizer-BioNTech COVID-19 Vaccine EUA” in the description section of the report.

V-Safe After Vaccination Health Checker

The CDC has launched the new V-safe After Vaccination Health Checker. V-safe web pages feature information on how to register and complete a V-safe health check-in (including step-by-instructions with images), troubleshooting, FAQs, and contact information for technical support. These web pages will be continuously updated with additional resources. Healthcare providers have a vital role in encouraging COVID-19 vaccine recipients to participate; please see the recommended provider/patient script below and this v-safe information sheet and poster:

The CDC has created a way for you to report how you feel after COVID-19 vaccination through a smartphone-based tool that uses text messaging and web surveys to check in with you. Here (or in your packet) is a V-safe information sheet with more details and simple instructions to sign up.

Recent & Upcoming Webinars

  • This webinar led by Dr. Jane Kelly, Assistant State Epidemiologist, SC DHEC, provides a helpful overview of the Pfizer vaccine product and vaccine administration considerations.
  • SC COVID-19 Virtual Grand Rounds Series has on-demand recordings available here.
  • The CDC has created an on-demand, self-paced training module for healthcare providers who will be administering Pfizer-BioNTech COVID-19 vaccine. This module will provide information on storage, handling, preparation, administration, and documentation of the Pfizer-BioNTech COVID-19 vaccine. Continuing education will be available for this module.